Warning! Waxing may cause hyperpigmentation. Most have all heard the tale of the friend, client, or relative that suffered from hyperpigmentation after getting waxied and swore they would never get waxed again. When it comes to hair removal, hyperpigmentation is one of the more traumatic side effects. It is characterized by an increase in melanin, or the substance that gives skin its color. To find the answers to minimizing it, waxers need to ask the right questions.