Study reveals synergistic powers of Lycoderm™ ingestible skincare extract

The blend of tomato and rosemary extracts in Lycoderm™ has a synergistic effect that may help balance skin cells’ response to environmental challenges, new research has found.

Developed to promote wellness from within, Lycored’s ingestible skincare extract contains a combination of carotenoids and polyphenols including lycopene, phytoene, phytofluene, and carnosic acid.

Previous research has shown that Lycoderm™ can benefit overall skin condition as well as visibly boosting radiance and reducing the appearance of lines and wrinkles.1 Now, a study published in Molecules has provided new insights into its molecular mechanism, further validating the blend’s ability to support skin health at the cellular level.2

The pre-clinical tests demonstrated that the phytonutrients in Lycoderm™ cooperate to inhibit inflammatory cytokines that lead to the degradation of skin collagen. Its patented combination of carotenoids and polyphenols was found to inhibit the secretion of the cytokines and balance oxidative stress far more effectively than either tomato extract or rosemary leaf extract alone.

Moreover, the study further substantiated the bioavailability of Lycoderm™. A group of young, healthy subjects began taking Lycoderm™ in addition to their regular diet, with blood tests taken two and three weeks after beginning supplementation. The results showed that the average plasma concentration of the major tomato carotenoids almost doubled.

As such, the study underlines the benefits of supplementation with tomato nutrients on top of a healthy diet, demonstrating relevant mechanisms of action that support health and beauty across all skin types and age groups.

Karin Hermoni, Head of Product and Science at Lycored, said: “When creating Lycoderm™, we were aiming for the ultimate mix of carotenoids naturally present in the tomato alongside the polyphenols in natural rosemary leaf extract. This research shines a light on how these phytonutrients work together to nourish the body from the inside out, helping to maintain skin health and wellness to achieve an ‘inner glow.’”

Lycoderm™ is a plant-based, clean-label solution that can be used in a wide range of dietary supplements and is GRAS for food and beverage use.

The full study, ‘Combined effects of carotenoids and polyphenols in balancing the response of skin cells to UV irradiation,’ can be viewed here:

1 Tarshish, E., Hermoni, K. & Schwartz, S.R. 'Effect of oral supplement “Lycopene” on reducing the signs of skin ageing' Clinical Pharmacology and Biopharmaceutics (2020)

2 Calniquer, G. et al. 'Combined effects of carotenoids and polyphenols in balancing the response of skin cells to UV irradiation' Molecules (2021)
(877) 592-6733


THE Tan Stick

Patent Pending, New Delivery System. Glides on smoothly, acts like an anti-aging serum, doesn't rub off on your clothes (or sheets) and leaves you feeling moisturized, and most importantly, provides a HEALTHY SUMMER GLOW. The Tan Stick is Cruelty-Free & Vegan, and contains NO dyes, NO artificial fragrance, NO parabens, and NO Phthalates. Curb Appeal Beauty is by women for women. FREE sample at


Repêchage® Vita Cura® CelluSea Lift™ Body Contour Cream

To help smooth, restore and renew the appearance of firmness in the skin, Repêchage®, pioneers in sustainably-harvested seaweed-based professional skin care since 1980, introduces the NEW! Vita Cura® CelluSea Lift™ Body Contour Cream.

The NEW! Vita Cura® CelluSea Lift™ Body Contour Cream utilizes an advanced natural biopolymer complex of Kappaphycus Alvarezii Extract and Caesalpinia Spinosa Fruit Extract, which, in studies, has displayed proven efficacy of its visibly lifting and smoothing effect. This rich cream is also powered by three Seaweed extracts, Caffeine and potent, skin-enhancing Coenzyme A to help smooth the appearance of the skin.

Together, these ingredients help to reduce the appearance of dimpled, orange-peel skin in all areas of concern, while a Grapefruit and Peppermint essential oil blend providing a stimulating and invigorating aroma. The NEW! Vita Cura® CelluSea Lift™ Body Contour Cream can be used as part of a healthy diet and exercise program to restore and renew the appearance of body contours.

And, for an even better experience, this cream can be used in conjunction with the Repêchage® LED Radio Frequency and EMS Skin Tightening Machine for deeper penetration into the superficial layers of the skin.

Key Ingredients:

Laminaria Digitata Extract
This seaweed extract is rich in 12 Vitamins, including B12, C, E, K and in beta-Carotene, 18 amino acids and 42 trace elements to help moisturize and improve the appearance of the skin tone.

Cocoa Seed Butter
Known for its very high emollient properties, Cocoa Butter is great at moisturizing the skin to prevent dry skin. It also contains various antioxidants known to help reduce the visible effects of free radicals.

Kappaphycus Alvarezii Extract and Caesalpinia Spinosa Fruit Extract
Biopolymers formed from a complex of Kappaphycus Alvarezii Extract and Caesalpinia Spinosa Fruit Extract has displayed proven efficacy of its visibly lifting and smoothing effect in previous studies.

Enteromorpha Compressa Extract
This yellow green seaweed is known to soothe the appearance of the skin.

Bupleurum Falcatum Root
Bupleurum, which is also known as ChaiHU, is an ancient herb that has been used in China for thousands of years.

This extract of the coffee plant is known to help visibly firm the surface layers of the skin.

Coenzyme A
Helps skin appear more resilient.

About Repêchage®: Since 1980, Repêchage® has created a full range of seaweed-based skincare products featured at top spas and salons globally. Forerunners in sea plant technologies and pioneers in seaweed treatments and cosmetics in the US, Repêchage® researchers seek out specific seaweeds beneficial for a range of skin care concerns. Our seaweed is sustainably harvested from the coast of Maine and then processed by our proprietary method in our Secaucus, NJ facility to deliver all the benefits from the sea to the skin.

1-800-248-SKIN (7546)


Hair & Scalp Health with Repêchage Hydra-Amino18 Hair Spa Serum Now Silicone Free

Repêchage®, the leading manufacturer of sustainably-harvested Seaweed based skin care brings the benefits of Seaweed to stressed, dry hair with the relaunch of the Repêchage® Hydra-Amino18® Hair Spa Serum.

Stress and poor diet can weaken the hair, causing breakage and hair loss.1 In these unprecedented times, studies have found that up to 72% of people in the United States say their lives have been disrupted by COVID-192, and seven out of ten people say they are experiencing the most stressful period of their lives.3

Used as a daily styling aid prior to drying to protect hair, or as an intensive conditioning treatment, this silicone-free hair serum provides a spa and salon-quality hair treatment at home, and is based on skin care ingredients, formulated with Repêchage®’s exclusive Laminaria Digitata Seaweed extract. Sustainably-harvested from the coast of Maine, this extract is a potent concentrated filtrate with 18 amino acids that act as building blocks of protein to restore the surface of stressed, damaged hair, while 12 vitamins and 42 trace elements and minerals infuse hair with shine, helping to restore and renew resiliency.

Rich with rich, nutritive botanical oils such as Marula Seed Oil, Jojoba Seed Oil, Coconut Oil and Safflower Seed Oil, as well as antioxidant Vitamin E, Hydra-Amino18® Hair Spa Serum locks in and restores hair’s essential moisture, leaving the hair surface smooth while helping to protect from further damage from heat styling and the environment.

“We have relaunched the Hydra-Amino18® Hair Spa Serum to provide the ability to practice important self-care to the hair with the powerful skin care benefits of Seaweed,,” says Repêchage® CEO and Founder Lydia Sarfati. “With this new silicone –free formula, the hair surface will be restored and fortified without being weighed down, and assisted in protection against the effects of the environment, heat styling as well as stress and poor diet.”


1-800-248-SKIN (7546)


Skin Care Blogs

Brands of the Month

  • Skin Script
  • Repechage
  • Celluma by Biophotas, Inc

Skin Care Articles