While stratum corneum desquamation may sound highly scientific and extremely complicated, it’s actually a normal physiological process. Skin cells are formed in the stratum germinativum, the deepest layer of the epidermis, then travel up to the dermis until they reach skin’s outermost layer, the stratum corneum. There, as corneocytes, which are dead cells filled with keratin protein, they exist until desquamation occurs. Desquamation is the shedding of individual dead skin cells, or small aggregates of these types of cells. During a 24-hour period, a person loses almost five thousand million skin cells.1
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