Corneobiology refers to a broad range of experimental studies focused on the anatomy, physiology and biology of the stratum corneum, focused specifically on the horny layer that is very unique to human beings.1 This science encompasses numerous studies that deal with immunology, endocrinology, neurobiology and psychology. Studies as early as 1964 showed that the horny layer membrane was a coherent tissue of cornified cells (corneocytes)…