Fibrocell Science, Inc., a gene therapy company focused on transformational autologous, cell-based therapies for skin and connective tissue diseases, today announced that the United States Food and Drug Administration (FDA) has granted allowance of its Investigational New Drug (IND) application for FCX-013 – one of the company’s gene therapy candidates – to begin clinical trials for the treatment of moderate to severe, localized scleroderma.
“We are pleased the FDA has granted allowance of our IND for FCX-013 to begin clinical trials for the treatment of moderate to severe, localized scleroderma, offering patients the potential for relief from this chronic, painful, and debilitating disorder,” said John Maslowski, president and chief executive officer of Fibrocell. “With no FDA-approved therapies available, we look forward to advancing FCX-013 into the clinic.”
Localized scleroderma is a chronic, autoimmune skin disorder characterized by excessive collagen deposition resulting in thickening of the dermis and underlying tissue. Moderate to severe forms of localized scleroderma can result in significant morbidity, including pain, restricted motion, disfigurement, and developmental issues. FCX-013 is an autologous fibroblast genetically modified to express matrix metalloproteinase 1 (MMP-1) – a protein responsible for breaking down collagen. FCX-013 incorporates Intrexon Corporation’s proprietary RheoSwitch Therapeutic System®, a biologic switch activated by an orally administered compound (veledimex) to control protein expression.
Fibrocell expects to initiate enrollment for an open label, single arm, phase ½, clinical trial in the third quarter of 2018. The primary objective of the trial is to evaluate the safety of FCX-013. Secondary analyses consist of several fibrosis assessments including histology, skin scores, ultrasound, and additional measurements of targeted sclerotic lesions and control sites at various time points up to 16 weeks post-administration of FCX-013. Ten patients with any subtype of localized scleroderma are targeted for enrollment (approximately five patients per phase). The phase one portion will enroll adult patients. Dosing for the first three adult patients will be staggered prior to dosing the rest of the trial’s population.
Fibrocell intends to include pediatric patients in the phase two portion of the trial after submission and approval of safety and activity data from the adult phase one patients to the FDA and the Data Safety Monitoring Board for the trial.
“The impact of localized scleroderma on patients, particularly children, can be devastating –affecting growth and mobility of their affected limbs,” said Alfred Lane, MD, chief medical advisor of Fibrocell and professor of dermatology and pediatrics (emeritus) at the Stanford University School of Medicine. “There are no approved therapies for localized scleroderma. Current treatments are aimed at impacting inflammation, but few options exist to treat the excessive collagen deposition in the skin and soft tissue, which may produce pain and limitation in motion and growth. With FCX-013, the goal is to bring relief to patients by targeting the abnormal collagen metabolism to improve skin function.”
The FDA has granted Orphan Drug designation to FCX-013 for the treatment of localized scleroderma. In addition, FCX-013 has been granted Rare Pediatric Disease designation for the treatment of moderate to severe, localized scleroderma. FCX-013 is being developed in collaboration with Intrexon Corporation, a leader in synthetic biology.
VB Cosmetics company, Dazzle Dry, announced that it is partnering with recognized, global non-profit, WeForest – an organization that engages with scientists, corporations, and other organizations to advance forest landscape restoration. WeForest will be working with Dazzle Dry specifically to help regenerate forests in the Khasi Hills of India.
“Dazzle Dry believes that beauty and wellness go hand in hand,” says VB Cosmetics Founder Dr. Vivian Valenty. “For us, partnering with WeForest to help communities in India’s Khasi Hills regenerate their forest was a natural fit. Now, every purchase our clients make doesn’t just give them healthier cosmetics, it gives us all a healthier planet.”
Through the newly launched partnership, Dazzle Dry will donate one new tree to WeForest for every purchase made on its site. Ultimately, with the assisted efforts of companies like Dazzle Dry, WeForest aims to restore the forests of the Khasi Hills and, in turn, support the communities that live there.
While this collaboration is expected to continue indefinitely, Dazzle Dry has also decided to kick-start its charitable efforts by releasing a specially-curated WeForest collection. Each purchase of these forest-inspired nail lacquers, including Breathe Free, You Rock, Spiritual Diva, Morning Dew, Dragonfly, and Me d’Forest Queen, will provide an additional tree to the WeForest project through the month of May.
To view the featured WeForest collection, visit dazzledry.com. For more information on Dazzle Dry’s partnership with WeForest, visit weforest.org/partner/dazzle-dry.
The Association of Holistic Skin Care Practitioners (AHSCP) will hold its 11th annual conference on Nov. 4 and 5 at Chicago’s Crowne Plaza O’Hare Hotel. It will feature extensive, hands-on learning opportunities and demonstrations, so registration will be limited this year. The AHSCP offers the latest protocols and trends in organic, non-invasive skin care, as well as continuing education for aestheticians and holistic skin care certification. Workshops and conferences sponsored by the AHSCP provide education on natural ingredients, demonstrations of European and Eastern methods for individualized skin care protocols, and networking opportunities. For more information, go to holisticskincarepractitioners.org or call 269-384-2170.
Eminence Organics celebrates their largest annual business conference July 20 through 22. This dynamic, yearly event unites over 200 Eminence team-members from around the world for three days of education, knowledge sharing, and celebration. Held in Vancouver, British Columbia the conference is designed to celebrate company wins and galvanize growth for the next 12 months.
In 2007, Make My Day Beautiful!®’s founder and CEO, Linda Litzinger Beck, and husband, Greg Beck, first became affiliates of The Barbara Sinatra Center For Abused Children, in Rancho Mirage, California. They experienced the Frank Sinatra Celebrity Invitational Golf Tournament weekend and visited The Center, which benefits from money raised at the annual (now 32 year old) event. Touring
The Center, they learned about the remarkable programs, counseling, and services provided for children and families in need. Learning that the skin care, makeup, and grooming products needed as part of the center’s Girls’ Self-Esteem Class were acquired “catch-as-catch-can,” Beck committed to design and gift custom, complete, age-appropriate kits of full-size products to accommodate the self-care teaching and post-classroom needs of each girl in the program.
Spring 2018 marks 10 consecutive years of fulfilling this commitment. In addition, the company became a supporting sponsor of multiple Sinatra Invitational Fashion Show/Luncheons and anniversary events, providing hundreds of personal gifts for each, as well as deluxe door prizes and silent auction gift boxes for Mrs. Sinatra’s guests. Though all involved are greatly saddened and missing the beautiful Barbara Sinatra, since her passing in 2017, her legacy lives on, perpetually, through the existence of The Center. Make My Day Beautiful!® is committed to supporting The Center in all ways possible.
Former Hand & Stone Director of Training, Doug Elman, joins Saltability – a spa industry vendor providing quality Himalayan salt stone treatments and products for spas – as the company’s director of education. Elman will work to educate spa partners on Saltability treatments, developed by spa industry veteran Ann Brown, that offer a more environmentally friendly, healthier alternative to traditional stone massage.
Just in time to welcome spring, Sanctuary Spa at Sanctuary on Camelback Mountain Resort & Spa has completed a top-to-bottom refurbishment and expansion that has introduced a fresh new look and features throughout. An intimate retreat, the celebrated spa features separate women’s and men’s spas, with a total of 12 indoor and outdoor treatment rooms and a private, stone-walled outdoor treatment room called Sanctum. Sanctuary Spa’s inspired redesign is the work of interior designer Lynne Beyer. Mark Philp, of Allen + Philps Architects, is the project architect.
Bioelements professional skin care is excited to announce the creation of a new advanced aesthetics initiative for 2018. Bioelements Pop-Up Education will bring the skin care company’s sought-after advanced education to select aesthetics institutions across the country. The New Age Spa Institute (NASI), a fully accredited school in Illinois that teaches to the highest standards and was founded to provide state-of-the-art education, is the first Bioelements Pop-Up Education partner school.
“We are extremely honored, humbled, and pleased to be a Bioelements Pop-Up Education partner school and help bring innovative education to aspiring students,” said Monika Machej, president of NASI and a CIDESCO Diplomat. “After Bioelements founder Barbara Salomone became my mentor years ago, I began to blossom and it is my duty to live up to the expectations of her wisdom by pouring knowledge into students so that they give back.”
“Bioelements was built on education. It is the heart of everything we do,” said Teresa Stenzel, Bioelements’ director of education. “Bioelements Pop-Up Education will allow us to bring our advanced aesthetics insights, techniques, and trend expertise to countless new aestheticians. We could not be more excited with this new partnership with the New Age Spa Institute, a truly world class aesthetics institution.”
Make Scents Natural Spa Line is pleased to announce a partnership with The Spa Mart. Powered by a community of millions, The Spa Mart is a wholesale distributor exclusive to the spa, wellness, and salon and spa education industries. The spa distribution company, headquartered in Georgetown, Texas, is dedicated to creating solution-driven partnerships that develop a culture of giving, gratitude, and valuing people.
“We have similar business philosophies,” said Make Scents Natural Spa Line owner, Heather J. Kreider. “It’s a partnership we absolutely love – and are proud to share the news. … The Spa Mart is a phenomenal partner. Their philosophy to help companies and individuals reach their full potential speaks to our clients who desire curated products that respect the health and well-being of their bodies and the planet. It just makes sense.”
Industry leader and founder of CA Botana, Dr. Dieter Kuster, passed away unexpectedly at the beginning of March 2018. Kuster was affectionately known as the “Einstein of Emulsion Technology.” With glowing skin and not a wrinkle or line on his face, he was his own best example of his innovative skin care research, which resulted in many new or advanced products and treatments.
Kuster was young at heart, in appearance, and demeanor, but also in his business approach. Always the scientist, Kuster was continuously investigating new, or better, formulations. One of his breakthrough achievements was the development of the highly-acclaimed Molecular Penetrator Alphasomes, an advanced delivery system to increase product effectiveness. Other pioneering work included target-specific enzymes and superior peptide technology.
Throughout his more than 50 years in the cosmetic trade, he developed over 4,000 products. He conducted clinical trials and product testing and was an internationally sought out lecturer in his field. Kuster was published in numerous trade publications and was the subject of many magazine and newspaper articles.
Kuster’s life was an authentic success story. Time and again, he triumphed over hardship and sorrow. His optimistic spirit and can-do attitude kept him moving forward in life and business in a positive direction.
Kuster leaves behind an incredible legacy of personal and professional achievement. He will not be forgotten.
On January 31, 2018, we gathered together to celebrate the life of Joel Gerson – my friend, my colleague, and my neighbor. He passed away at age 83 after a wonderful life and groundbreaking career in aesthetics.
Joel Gerson was a prolific representative of the aesthetics industry. In addition to having been an inspiration to countless incoming students, he was an international ambassador of American aesthetics. His influence reached every corner of our industry. His charm and whit preceded him and his passing is a great loss to all who love the profession – and the man. - DERMASCOPE Magazine
Joel’s textbook, “Milady’s Standard Textbook for Professional Estheticians,” forever changed the field of aesthetics. He was among the first to put the industry’s practices down in text, which provided benchmarks to be followed. In doing so, Joel wrote so much more than a textbook – he created direction and standards that may have shaped the industry. Without his work, the field may not have become what it is today.
For me, Joel’s accomplishments cannot be separated from my memories of the man himself. He had a unique personality and strong sense of humor – one never knew what he was going to say. I remember when he introduced me as a speaker at a beauty congress. After explaining to the audience that I needed no introduction, he stopped in surprise and announced, “Wow, Annette! You’ve lost so much weight – tell us how you did it.”
Joel’s brother, Richard, organized the gathering that celebrated his life. Although Richard lived in California, he and Joel remained close their whole lives. Naturally, Richard hosted the celebration in Joel’s apartment building on 73rd and Madison in Manhattan. It was there that Joel happily spent his last days. He never missed one of the building’s weekly Wednesday Happy Hours in the special event room, where he socialized with all his neighbors and friends, while his friend Scott played the piano. Scott returned that evening to play for all of us one last time, along with colleague Paul Dykstra, CEO of Chicago Cosmetologists, who flew in especially for the occasion.
The crowd in the room that evening was a “who’s who” of the aesthetics industry. Susanne Warfield, executive director of the NCEA, was there celebrating the life of our close friend. For years, Joel and I got together with Susanne to celebrate our birthdays at Capsouto Frères, an old restaurant downtown, by sipping on dirty martinis at the bar before discussing the latest advancements in skin care over dinner and chocolate soufflés. Even after his retirement, Joel’s passion for the field never waned – and neither did his penchant for a colorful comment. Conversations with Joel were always entertaining and his sharp sense of humor left an impression on everyone he met.
I was caught off guard and broke into laughter, forgetting any apprehension I may have had about addressing the group. Thanks to Joel and his quick quip, I was immediately both knocked off balance and flushed with confidence. At the time, I was surprised, but looking back, I should have expected that from him. Joel always kept everyone on his toes with his wit and he had an amazing way of genuinely building up others and helping them succeed.
Lydia Safarti, owner of Repechage Skin Care, spoke about her friendship with Joel. Joel was there to share her joy when her two daughters got married and to support her when her parents passed. For Lydia, Joel was a friend who became family.
A couple of instructors from the Christine Valmy Esthetics School were also in attendance. Joel was one of the first skin care teachers at the school when it opened in 1965, which made it especially meaningful that they came to pay their respects.
Joel, like I, wanted standards in the industry. Without a license and guidelines, there could be no profession. As the science of aesthetics progressed, and, especially, as it became more medically-advanced, education and licensure became a must. Partly because we shared that passion, and partly because we purely enjoyed each other’s company, Joel and I had a standing Sunday brunch date for years.
I also had the pleasure of hosting Joel many times as a guest lecturer at Atelier Esthétique; and each time, my students were fascinated by his personality, knowledge, and passion for teaching about skin care.
While Joel slowed down a bit at the end of his life, he remained as involved as he could in the field for as long as he could, simply because he loved it. He loved the people, the business, the science, and the developments that continued to be made.
For me, Joel’s passing has left a void in the industry almost as large as the wonderful impression he made on all of us during his life.
Members of AIA’s Academy of Legends look back on Joel Gerson:
I met Joel Gerson in the early 1970s at Christine Valmy. We both were much younger and starting out. My first impression of him was how much of a visionary he was. I have the highest regard for him. Our paths crossed often through the years. The industry is fortunate to have him as an achiever and incredible author who brought the most important information to the forefront in his textbooks. He created the skin care bible for our industry and for that we are all grateful.”
Lia Schorr, owner of Lia Schorr Institute, inducted into the AIA Academy of Legends in 1991
A consummate professional, he raised the bar on industry standards and education. His contributions will be remembered as his work continues to influence aestheticians around the world.” Rhonda Allison, founder and CEO of Rhonda Allison Cosmeceuticals, inducted into the AIA Academy of Legends in 2016
Joel Gerson lived a few blocks away from where I had my first office and spa on the upper east side of Manhattan, before I moved to California. When we met, I didn’t know who he was because I had recently moved from Paris to New York.
One afternoon, Joel walked into my brownstone’s retail store with an endearing smile on his face. The place was crowded. He walked straight to me, introduced himself, and said, ‘I’m Joel Gerson and I’m on the cover of this magazine,’ [holding up DERMASCOPE].
In that moment, I met both a man with whom I would have insightful conversations for years to come who helped elevate our industry, and DERMASCOPE – the magazine that influenced our industry so much.
I remember every detail of that first meeting. Joel was humble, easy going, and unselfish – sharing knowledge with aestheticians everywhere. I’m sad Joel is gone, but he remains a positive influence as an educator and warm human being.” Catherine Atzen, founder of ATZEN Superior to Organic® Skin Care, inducted into the AIA Academy of Legends in 2016
Joel was an educator who brought out the best in his aesthetic students and demanded they practice with the utmost perfection. Joel was serious about aesthetics and helped bring respect to our industry – that aestheticians are not cream pushers, but as valued as medical personnel.” Christine Heathman, L.M.E, founder of GlyMed Plus, inducted into the AIA Academy of Legends in 2008
Joel and I shared so many things – a birthday, our love of the skin care industry, and a desire to share our knowledge. Joel always made himself available for lectures and teaching events for the Skin Care Association of America. We had so many trade show and teaching adventures over the years, as professional skin therapy developed in the United States. He was a true innovator and friend.”
Kay Acuazzo, past president of the Skin Care Association of America, inducted into the AIA Academy of Legends in 1989
Joel Gerson was my friend, my dear mentor, and my inspiration. He was a true pioneer in esthetic education, the author of the definitive ‘Standard Textbook for Professional Estheticians,’ aesthetic examiner for the New York Department of State, and the leading educator responsible for maintaining standards of excellence in aesthetics. Yet, Gerson was more than a professional mentor. Since 1974, Joel was my friend, part of my family – my “mishpucha” – and I have been blessed to know him. He never missed holidays with David and me. I will always keep him in my heart and will miss him very, very dearly. May his soul rest in peace.” Lydia Sarfati, founder and CEO of Repêchage, inducted into the AIA Academy of Legends in 1991
Joel was one of the people who wanted to see my demonstration in New York on my first visit. It was always a pleasure to meet him on my visit to the United States. He was an influence in the skin care profession. I hope the long journey brings him peace and well-deserved rest.” Eve Taylor, O.B.E., founder of Eve Taylor North America, inducted into the AIA Academy of Legends in 2014
Joel was a pioneer and visionary in aesthetics education. He set a standard of professionalism and theory that created the foundation for the aesthetics industry today. I considered him a friend and colleague. He will be fondly remembered and forever in the hearts of all who knew him.” Catherine E. Hinds, founder of the Catherine Hinds Institute of Esthetics, inducted into the AIA Academy of Legends in 1990
Joel Gerson was a pioneer in the skin care industry. I loved his lectures. They were always easy to understand. Most of all, his lectures were amusing and funny. I used his aesthetics book in my skin care classes. Joel will be remembered for his dry wit and fun personality.” Letti Lynn, aesthetics director and owner at Letti Lynn Skin Care & Cosmetics, inducted into the AIA Academy of Legends in 1987
One of the biggest struggles of an industry like ours is consistency, cohesiveness, and a unified front to push forward and continue to raise the bar. Joel was at the forefront of unifying the aesthetics profession to commit to core education and the continued growth of knowledge and expertise.” Michelle D’Allaird-Brenner, L.E., owner of Aesthetic Science Institute, inducted into the AIA Academy of Legends in 2017
Joel Gerson championed the writing of a pioneering textbook. I have a signed copy of his original. When I wrote ‘Skin Care: Beyond the Basics,’ he called me and was so supportive. Joel always had the advancement of the profession at heart. He had an amazing sense of humor. We enjoyed many lunches and dinners together discussing the progress of the industry. He was a mentor and trailblazer. I will miss him and always hold him in great respect for his boldness in establishing an anchor in aesthetics education.” Mark Lees, founder of Mark Lees Skin Care, inducted into the AIA Academy of Legends in 1990
NovaLash’s annual LASHOff was held in Houston, Texas in 2018. At the event, the Lash Artist of the Year was selected – an honor bestowed on the top eyelash artist from the company’s international roster of eyelash extension professionals. Finalists for this award submit a collection of videos and photographs to showcase skill and an eye for giving clients the perfect NovaLash look. Tonje Fjeldberg Elshaug of ĽAlfáz del Pi, Spain was named 2018 Lash Artist of the Year. “To win Lash Artist of the Year is truly my dream come true,” Elshaug said. “It makes me feel that anything is possible. If you never give up, have big dreams, and work hard, you can achieve your dreams.” As Lash Artist of the Year, Elshaug will receive over $25,000 in cash and prizes as well as advertising, marketing, and travel opportunities with NovaLash.
In 2022, a new commercial hub for companies from the cosmetics industry will be erected in Pascalstrasse, a business park in Aachen, Oberforstbach, Germany. Janssen and Inspira are building an office building there as a multipurpose hall for packaging and shipping cosmetics. In this building the products will be shipped to consumers as well as spas in Germany, France, and England. Janssen Cosmetics GmbH has been based in this area since 2000. The company is a worldwide distributor of cosmetic products for beauty salons and spas and currently employs 34 people. As the company grows, two new buildings will be added to the present headquarters in Aachen Oberforstbach – an administrative building, with a new training center, and a building for logistics, in order to meet the demands of an increasing number of shipments. This development, along with increasing sales, will create more jobs in the area and a collaboration with the regional, economic-development program, Regionales Wirtschaftsförderungsprogramm (RWP.NRW).
As of this month, natural and organic, professional skin care brand, Eminence Organic Skin Care, has reached a momentous mark, having planted 10 million trees through their successful Forests for the Future program. Since 2012, Eminence has planted a tree for every retail product sold. The trees are planted through the brand’s Forests for the Future program, which helps train farmers in developing countries on how to build productive and sustainable Forest Gardens. The development of these Forest Gardens in rural communities empowers local people to restore their environment, grow their own food, and build a sustainable income and future their communities. Eminence is proud to contribute to the development of these Forest Garden Projects. A single tree produces approximately 260 pounds of oxygen per year, while also providing a habitat for biodiversity and helping combat climate change.