Human skin, like all other organs, undergoes chronological aging. Skin aging is characterized histologically by irregularly dispersed melanocytes, elastosis, reduction, and alterations in collagen and accumulation of a variety of lipid-derived pigments such as chromolipoids and lipofuscins. These internal and silent histological shifts manifest clinically in the skin and the visible benchmarks are identified by fine and coarse wrinkling, roughness, laxity, dryness, sallowness, pigmentary moddling,…